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R1072-2 - ZBTB1 (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 82 I 75, 90 kDa Uniprot ID: Q9Y2K1 Background: Lymphocytes arise from multipotent progenitors in the bone marrow deviating from the myeloid lineage and completing their differentiation under the influence of a suite of transcriptional regulators, including Ikaros, Pax5, Notch1 and the BTB-ZF (Broad complex, Tramtrack, and Bric à brac–zinc finger) family of proteins. Zinc finger and BTB domain-containing protein 1 (ZBTB1) is a 713-aa member of the POK (POZ [Poxviruses and zinc finger] and Krüppel) or BTB-ZF family of transcriptional regulators. ZBTB1 has been shown to be essential for T cell development and also for the development of B and NK cells under competitive conditions. Other Names: Zinc finger and BTB domain-containing protein 1, zinc finger and BTB domain containing 1, KIAA0997, ZNF909 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing C-terminal region of human ZBTB1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from(A) human HeLa, (B) human Jurkat; using anti-ZBTB1 (C) (R1072-2) at RT for 2 h.
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