Products

R2355-2 - SIRT4 (C) Antibody, Rabbit Polyclonal

Catalog No. R2355-2
Product Name SIRT4 (C) Antibody, Rabbit Polyclonal
Price $219
  
 

Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 35 I 40 kDa                                                     Uniprot ID: Q9Y6E7 


Background:

SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

Other Names:

NAD-dependent protein deacetylase sirtuin-4, NAD-dependent ADP-ribosyltransferase sirtuin-4, Regulatory protein SIR2 homolog 4, SIR2-like protein 4, SIR2L4

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing C-terminal region of human SIRT4. Antibodies were purified by affinity purification using immunogen.                                                                    

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

SIRT4 Antibody Western (Abiocode)

Fig 1. Western blot of total cell extracts from
(A) mouse brain, (B) mouse thymus, (C) human
HeLa, (D) human Jurkat; using anti-SIRT4 (C)
(R2355-2) at RT for 2 h.