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R0823-1 - FZD7 (N1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 64 kDa Uniprot ID: O75084 Background: Frizzled-7 (FZD7) is a multi-pass membrane belonging to the proteinG-protein coupled receptor Fz/Smo family. FZD7 is a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Other Names: Frizzled-7, FzE3, Fz-7, hFz7 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing N-terminal region of human FZD7. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts fromA) mouse brain, B) human HeLa, C) human Jurkat; using anti-FZD7 (N1) (R0823-1) at RT for 2 h. |