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R2276-2 - SOD1 (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 16 kDa Uniprot ID: P00441 Background: Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. SOD1 is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occurring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. Mutations in the SOD1 gene have been implicated as causes of familial amyotrophic lateral sclerosis. Other Names: ALS, ALS1, IPOA, Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SOD1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extractsA) human HeLa, B) human Jurkat; using anti-SOD1 (C) (R2276-2) at RT for 2 h. |