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R0578-2 - MC4R (N2) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 37 kDa Uniprot ID: P32245
Background: Melanocortin receptor 4 (MC4R) is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. MC4R is a receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. Defects in MC4R are a cause of obesity. Other Names: Melanocortin receptor 4, MC4-R Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MC4R. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:5,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data: Fig 1. Western blot of total cell extracts from mouse brain, using Ab (R0578-2) at RT for 2 h.
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