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Quantity: 100 ul                                                                                         Application: WB

Predicted | Observed MW: 93 | 110 kDa                                                     Uniprot ID: Q03167

Background:

Transforming growth factor beta receptor type 3 (TGFBR3) is a membrane glycoprotein that often functions as a co-receptor for other TGF-beta receptor superfamily members. TGFBR3 binds to TGF-beta. TGFBR3 could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of TGFBR3 has been observed in various cancers.

Other Names:

Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human TGFBR3. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: