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Quantity: 100 ul                                                                                        Application: WB

Predicted | Observed MW: 76 | 128 kDa                                                    Uniprot ID: P49418

Background:

Amphiphysin (AMPH) encodes a protein associated with the cytoplasmic surface of synaptic vesicles. AMPH may participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. It may control the properties of the membrane associated cytoskeleton. A subset of patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms, who were also affected by breast cancer are positive for autoantibodies against AMPH.

Other Names:

Amphiphysin, AMPH1

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human AMPH. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: