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Quantity: 100 ul                                                                                            Application: WB

Predicted I Observed M.W.: 94 kDa                                                            Uniprot ID: P42226

Background:

Signal transducer and activator of transcription 6 (STAT6) is a member of the transcription factor STAT family involved in interleukin-4 signalling. STAT6 contains one SH2 domain and carries out a dual function: signal transduction and activation of transcription. Upon stimulations such as IL-4 and IL-3, STAT6 is Tyrosine-phosphorylated, forms a homodimer or a heterodimer with a related family member and translocates into the nucleus, where it binds to DNA and activates transcription of downstream genes.

Other Names:

Signal transducer and activator of transcription 6, IL-4 STAT

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human STAT6. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: