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M0003-1 - PIASy (C) Antibody, Mouse Monoclonal
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Quantity: 100 ul Application: WB
Predicted M.W.: 56 kDa Uniprot ID: Q8N2W9
Isotype: mouse IgG1 Clone: 7B8
Background:
Protein inhibitor of activated STAT protein gamma (PIASy) functions as an E3 small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. PIASy functions as a transcriptional co-regulator in numerous cellular pathways, including the STAT pathway, the p53 pathway and the Wnt pathway. PIASy is also involved in gene silencing.
Other Names:
FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6, PIAS4
Source and Purity:
Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PIASy. Antibodies were purified by Caprylic Acid- Ammonium Sulfate precipitation.
Storage Buffer and Condition:
Supplied in 1 x PBS (pH 7.4), 40% Glycerol, 0.02% Thimerosal. Store at -20 °C. Stable for 6 months from date of receipt.
Species Specificity:
Human, Mouse
Tested Applications:
WB: 1:1,000-1:5,000 (detect endogenous protein*)
*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data:
Fig 1. Western blot of total cell extracts from mouse embryonic fibroblasts (MEFs) , using Ab (M0003-1) at RT for 2 h. |