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Quantity: 100 ul                                                                                        Application: WB

Predicted | Observed MW: 70 | 80 kDa                                                     Uniprot ID: Q12778 

Background:

Forkhead box protein O1 (FOXO1) is a transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, FOXO1 mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. FOXO1 triggers death of postmitotic neurons when phosphorylated by CDK1. FOXO1 activates transcription of PMAIP1.

Other Names:

Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FKHR, FOXO1A

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human FOXO1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: