Abiocode Logo
Products
Contact Us
- Telephone:
1-818-707-0309 - E-Mail:
Abiocode@Abiocode.com
R2159-vp - LRP8 (vPairTM) Antibodies
|
Predicted I Observed M.W.: 106 kDa Uniprot ID: Q14114 Application: WB Quantity: 50 ul LRP8 (C1) (R2159-1) Rabbit Polyclonal Antibody & 50 ul LRP8 (C2) (R2159-2) Rabbit Polyclonal Antibody Product Introduction: vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Background: LRP8 is cell surface protein that plays roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. LRP8 plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of LRP8 may be a marker for major depressive disorder. Defects in LRP8 are a cause of myocardial infarction type 1. Other Names: Low-density lipoprotein receptor-related protein 8, LRP-8, Apolipoprotein E receptor 2, APOER2 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing 2 distinct C-terminal regions of human LRP8. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from(A, C) human HeLa, (B, D) human Jurkat; using 2 independent Abs against 2 distinct regions of LRP8 at RT for 2 h. |