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R0808-1 - LRRC7 (M) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB, IP
Predicted I Observed M.W.: 172 kDa Uniprot ID: Q96NW7 Background: LRRC7 is required for normal synaptic spine architecture and function. LRRC7 is also necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. LRRC7 interacts with CAMKII, CNKSR2, DLG4, and CTNND2/Catenin delta-2. LRRC7 forms a complex with N-cadherin through CTNND2. Other Names: Leucine-rich repeat-containing protein 7, Densin-180, Protein LAP1, KIAA1365, LAP1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human LRRC7. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) IP: 1:100-1:200
*: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. A) Western blot of total cell extracts from mouse brain; using anti-LRRC7 (M) (R0808-1) at RT for 2 h. B) Total extracts from mouse brain were immunoprecipitated with IgG or anti-LRRC7 (M) (R0808-1); followed by WB with the same Ab. |