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Predicted M.W.: 224 kDa                                                                              Application: WB

Uniprot ID: Q6N021 (human) & Q4JK59 (mouse)            

Quantity:        20 ul TET2 (N1) (R1086-1) Rabbit Polyclonal Antibody

                      20 ul TET2 (C1) (R1086-3) Rabbit Polyclonal Antibody

                      20 ul TET2 (N2) (R1086-4) Rabbit Polyclonal Antibody

                      20 ul TET2 (M) (R1086-5) Rabbit Polyclonal Antibody

                      20 ul TET2 (C2) (R1086-6b) Rabbit Polyclonal Antibody     

Background:

TET2 is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). 5-hydroxymethylcytosine may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. TET2 plays an important role in myelopoiesis, and defects in TET2 gene have been associated with several myeloproliferative disorders.

Other Names:

Methylcytosine dioxygenase TET2, KIAA1546

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing the various regions of human (R1086-1 and R1086-3) or mouse (R1086-4, R1086-5, R1086-6b) TET2 as indicated in Figure 1 (see below). Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Species Specificity:

Human, Mouse 

Product Data: