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R2803-2 - MPL (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 71 I 75-85 kDa Uniprot ID: P40238 Background: Myeloproliferative leukemia protein (MPL) is a single-pass transmembrane protein also known as Thrombopoietin receptor (TPOR). MPL is a receptor for thrombopoietin, which belongs to the type I cytokine receptor family. MPL may represent a regulatory molecule specific for TPO-R-dependent immune responses. MPL deficient mice were severely thrombocytopenic, emphasizing the important role of MPL and thrombopoietin in megakaryocyte and platelet formation. Other Names: Thrombopoietin receptor, TPO-R, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110, TPOR Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing C-terminal region of human MPL. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts fromA) mouse thymus, B) human HeLa, C) human Jurkat; using anti-MPL (C) (R2803-2) at RT for 2 h. |