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Quantity:        50 ul SYP (C) (R0152-1) Rabbit Polyclonal Antibody &

                      50 ul SYP (M) (R0152-2) Rabbit Polyclonal Antibody

Product Introduction:

vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.

Background:

Synaptophysin (SYP) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.  It is possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.  Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP).  

Other Names:

MRXSYP, Major synaptic vesicle protein p38

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing either the C-terminal [SYP (C) (R0152-1)] or the middle region [SYP (M) (R0152-2)] of human SYP.  Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, mouse

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: