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R2886-1 - IREB2 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 105 kDa Uniprot ID: P48200 Background: Iron-responsive element-binding protein 2 (IREB2) is an RNA-binding protein that belongs to the aconitase/IPM isomerase family. IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Other Names: Iron-responsive element-binding protein 2, IRE-BP 2, Iron regulatory protein 2, IRP2 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human IREB2. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts fromA, C) human HeLa; B) human Jurkat; using 2 independent Abs against 2 distinct regions of human IREB2at RT for 2 h. |