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R3338-2 - PIRB (C2) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 93 I 120 kDa Uniprot ID: P97484 Background: Paired immunoglobulin-like receptor B (PIRB) may act as a receptor for class I MHC antigens. PIRB becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. PIRB down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). Other Names: Leukocyte immunoglobulin-like receptor subfamily B member 3, LIR-3, Leukocyte immunoglobulin-like receptor 3, Cell-surface glycoprotein p91, Paired immunoglobulin-like receptor B, PIR-B, Lilrb3 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of mouse PIRB. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Mouse Tested Applications: WB: 1:500-1:2,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: from mouse brain; using anti-PIRB (C2) (R3338-2) at RT for 2 h. |