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Quantity: 100 ul                                                                                 Application: WB

Predicted | Observed MW: 47 kDa                                                    Uniprot ID: P26367

Background:

Paired box protein Pax-6 (PAX6) is a transcription factor that belongs to the paired homeobox family. PAX6 has important functions in the development of the eye, nose, central nervous system and pancreas. It is required for the differentiation of pancreatic islet alpha cells. Defects in PAX6 are the cause of aniridia (AN), Peters anomaly (PAN), keratitis hereditary (KERH), coloboma of iris choroid and retina (COI), coloboma of optic nerve (COLON), bilateral optic nerve hypoplasia (BONH), and niridia cerebellar ataxia and mental deficiency (ACAMD).

Other Names:

Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, AN2

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human PAX6. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: