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R0709-2 - MMP27 (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted | Observed MW: 59 | 49 kDa Uniprot ID: Q9H306 Background: Matrix metalloproteinase-27 (MMP27) belongs to the peptidase M10A family. Matrix metalloproteinases (MMPs) degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens. MMPs are secreted by tumor cells themselves or by surrounding stromal cells stimulated by the nearby tumor. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs leads to enhanced cancer cell invasion. Other Names: Matrix metalloproteinase-27, MMP-27 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human MMP27. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:500-1:2,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from (A) mouse brain and (B) human AF10, using Ab (R0709-2) at RT for 2 h. |