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Quantity: 100 ul                                                                                             Application: WB

Predicted | Observed MW: 40 | 40, 50 kDa                                                 Uniprot ID: P49238

Background:

CX3C chemokine receptor 1 (CX3CR1) is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family, which is expressed in lymphoid and neural tissues. CX3CR1 is a receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. CX3CR1 acts as a coreceptor with CD4 for HIV-1 virus envelope protein. Variations in CX3CR1 are associated with rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).

Other Names:

CX3C chemokine receptor 1, C-X3-C CKR-1, CX3CR1, Beta chemokine receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine receptor, G-protein coupled receptor 13, V28, CMKBRL1, GPR13

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human CX3CR1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: