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Quantity: 100 ul                                                                              Application: WB

Predicted I Observed M.W.: 47 I 58 kDa                                         Uniprot ID: O14733

Background:

MAP2K7 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MAP2K7 specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. MAP2K7 is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses.

Other Names:

JNKK2, MEK7, MKK7, PRKMK7, SKK4

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MAP2K7. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: