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Predicted | Observed MW: 29 | 38 kDa                                                       Uniprot ID: P15407 

Application: WB

Quantity:        50 ul FOSL1 (C1) (R0844-2) Rabbit Polyclonal Antibody &

                      50 ul FOSL1 (C2) (R0844-3) Rabbit Polyclonal Antibody

Product Introduction:

vPair^TM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPair^TM antibodies in the same assay can validate signal specificity since vPair^TM antibodies recognize two independent epitopes of the same protein. Different sets of vPair^TM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.

Background:

Fos-related antigen 1 (FOSL1) is a heterodimer belonging to the bZIP family and the Fos subfamily. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

Other Names:

Fos-related antigen 1, FRA-1, FRA1

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion protein containing 2 distinct C-terminal regions of human FOSL1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt. 

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: