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R0069-1 - HP1-gamma (M) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 21 kDa Uniprot ID: Q9DCC5 Background: Heterochromatin protein 1-gamma (HP1-gamma) belongs to the heterochromatin protein family. It may be involved in transcriptional silencing in heterochromatin-like complexes. HP1-gamma binds to histone H3 tails methylated at ‘Lys-9’ (H3K9me), leading to epigenetic repression. It binds with lamin-B receptor, associating heterochromatin with the inner nuclear membrane. HP1-gamma is involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Other Names: cbx3, hech, xhp1g, hp1hs-gamma Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of mouse HP1-gamma. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:5,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from human heLa, using Ab (R0069-1) at RT for 2 h. |