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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 51 I 56 kDa                                                     Uniprot ID: Q8N2H9

Background:

PELI3 catalyzes the covalent attachment of ubiquitin moieties onto substrate proteins. PELI3 is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. PELI3 mediates 'Lys-63'-linked polyubiquitination of IRAK1. PELI3 can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. PELI3 is highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach.

Other Names:

MGC35521

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human PELI3. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications. 

Product Data: