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Quantity: 100 ul                                                                     Application: WB

Predicted M.W.: 55 kDa                                                        Uniprot ID: P15336

Background:

Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins.  It binds to the cAMP-responsive element (CRE), which is an octameric palindrome.  It has the ability to form a homodimer or a heterodimer with c-Jun and stimulate CRE-dependent transcription.  ATF2 is also a histone acetyltransferase that specifically acetylates histones H2B and H4 in vitro, therefore it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.                                                                      

Other Names:

Cyclic AMP-dependent transcription factor ATF 2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CRE-BP1, CREB2, HB16, MGC111558, TREB7

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human ATF2.  Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: