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R3260-2 - SLX4 (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 200 I 170 kDa Uniprot ID: Q8IY92 Background: Structure-specific endonuclease subunit SLX4 (SLX4) belongs to the SLX4 family and is a regulatory subunit that interacts with and increases the activity of different structure-specific endonucleases. SLX4 has several distinct roles in protecting genome stability by resolving diverse forms of deleterious DNA structures originating from replication and recombination intermediates and from DNA damage. Other Names: Structure-specific endonuclease subunit SLX4, BTB/POZ domain-containing protein 12, BTBD12, KIAA1784, KIAA1987 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SLX4. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:500-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extractsfrom A) mouse thymus, B) human HeLa, C) human Jurkat; using anti-SLX4 (C) (R3260-2) at RT for 2 h. |