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Quantity: 100 ul                                                                     Application: WB

Predicted M.W.: 100 kDa                                                       Uniprot ID: P19022

Background:

Cadherin 2, type 1, N-cadherin (neuronal) (CDH2) belongs to the cadherin superfamily, which are calcium dependent cell adhesion molecules.  CDH2 has five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.  They preferentially interact with themselves in a hemophilic manner in connecting cells.  CDH2 functions during gastrulation and is required for establishment of left-right asymmetry.  CDH2 is also involved in certain central nervous system synapses such as presynaptic to postsynaptic adhesions.  

Other Names:

CD325, CDHN, CDw325, NCAD, N-cadherin

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human CDH2.  Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: