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Quantity: 100 ul                                 Application: WB

Predicted M.W.: 12 kDa                     Uniprot ID: P55854

Background:

SUMOylation is a post-translational modification in which Small ubiquitin-related modifers (SUMOs) are covalently conjugated to target proteins. Protein SUMOylation is involved in many cellular processes, including nuclear transport, transcriptional regulation, DNA replication and repair and signal transduction.  The mammalian SUMO family is mainly consistent of 3 isoforms: SUMO1, SUMO2 and SUMO3.  While SUMO2 and SUMO3 share about 46% of sequence similarity with SUMO1, they share a 96% similarity between each other.  In addition, SUMO1 is conjugated to protein substrates at steady states, while conjugation by SUMO2/3 is inducible in response to various cellular stresses, such as oxidative stress and heat shock.

Other Names:

SMT3A, SMT3H1, SUMO-3

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing human SUMO3. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: