Products

R0240-1 - PRSS1 (N) Antibody, Rabbit Polyclonal

Catalog No. R0240-1
Product Name PRSS1 (N) Antibody, Rabbit Polyclonal
Price $219
  
 

Quantity: 100 ul                                                                                        Application:  WB

Predicted M.W.: 27 kDa                                                                            Uniprot ID: P07477


Background:

PRSS1 is also known as Trypsin-1, which belongs to the peptidase S1 family. PRSS1 has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.  Defects in PRSS1 are a cause of pancreatitis (PCTT), a disease characterized by the presence of calculi in pancreatic ducts and it causes severe abdominal pain attacks.

Other Names:

Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, TRP1, TRY1, TRYP1

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human PRSS1.  Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:5,000 (detect recombinant protein)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

PRSS1 Antibody Western (Abiocode)

Fig 1.  Western blot of total cell extracts
from mouse pancreas, using Ab (R0240-1)
at RT for 2 h.