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R0240-1 - PRSS1 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 27 kDa Uniprot ID: P07477 Background: PRSS1 is also known as Trypsin-1, which belongs to the peptidase S1 family. PRSS1 has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT), a disease characterized by the presence of calculi in pancreatic ducts and it causes severe abdominal pain attacks. Other Names: Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, TRP1, TRY1, TRYP1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human PRSS1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:5,000 (detect recombinant protein) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data: Fig 1. Western blot of total cell extracts from mouse pancreas, using Ab (R0240-1) at RT for 2 h.
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