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Quantity: 100 ul                                                                                 Application: WB

Predicted | Observed MW: 61 kDa                                                     Uniprot ID: P16297

Background:

Interleukin-2 receptor subunit beta (IL2RB) is a single-pass type I membrane protein, which belongs to the type I cytokine receptor family. IL2RB is a receptor for interleukin-2 and contains 1 fibronectin type-III domain. IL2R exists in 3 different forms: a high affinity dimer of the alpha and beta subunits, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. IL2RB is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Other Names:

Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, p75, CD122

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of mouse IL2RB. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: